Research Associate, Biomarker
Company Overview
Avidity Biosciences is pioneering a new class of oligonucleotide-based therapies called AOCs designed to overcome the current limitations of oligonucleotide therapies in order to treat a wide range of serious diseases. We utilize our proprietary AOC platform to design, engineer and develop therapeutics that combine the tissue selectivity of monoclonal antibodies (mAbs) and the precision of oligonucleotide-based therapies in order to access previously undruggable tissue and cell types and more effectively target underlying genetic drivers of diseases. We are passionate about the impact of every employee in bringing these potentially transformative therapeutics to patients in need. Make a difference with us.
Job Summary
We are seeking a Research Associate focused on assay development to join the Biomarker team at Avidity Biosciences in La Jolla, CA. This position will require hands-on lab work with responsibility for both working with in-vitro models and processing and analyzing biosamples (blood and tissues). The ideal candidate will be able to assist in the development of novel methods for biomarker discovery and development. The ideal candidate is expected to set up and execute experiments with minimal supervision, to be a strong team player who enjoys scientific discovery and to communicate and collaborate in a fast-paced interdisciplinary environment. Title and compensation will be commensurate with the candidate’s experiences.
Essential Duties and Responsibilities:
- Develop clinical biomarker assays with an emphasis on molecular biology- and sequencing-based approaches
- Facilitate relationships with external service providers, including method transfer, method development, method validation, and sample analysis in a GLP environment
- Design and perform experiments, analyze experimental data, report results, and provide feedback on appropriate next steps such as assay optimization or follow-up experiments
- Demonstrate effective presentation and verbal communication at internal meetings as well as clear written communication
Qualifications:
- BS or MS in Biology, Biochemistry, or related discipline with at least 2 years of laboratory experience
- Prior hands-on lab experience with various laboratory techniques including RNA isolation, RT-qPCR, ddPCR, RNA sequencing, cloning
- Direct experience with immunoprecipitation, immunoblotting, ELISA, density gradient isolation
- Cell culture experience
- Prior knowledge in developing biomarker assays in GLP environment for clinical programs is a plus
- Independence and ability to both conduct self-directed research and work effectively in a dynamic environment with a diverse team of coworkers
- Strong organization and record keeping skills
- Solid written and oral communication skills, enthusiasm, integrity, exceptional problem-solving skills, self-motivation, strong interpersonal skills, and attention to detail are necessary